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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF9
All Species:
6.36
Human Site:
Y300
Identified Species:
12.73
UniProt:
O60383
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60383
NP_005251.1
454
51444
Y300
Q
E
R
S
L
S
A
Y
P
V
G
E
E
A
A
Chimpanzee
Pan troglodytes
XP_527008
455
51476
Y301
Q
E
R
S
L
S
A
Y
P
V
G
E
E
A
A
Rhesus Macaque
Macaca mulatta
XP_001101902
271
31418
E122
F
T
F
N
S
Q
F
E
F
G
K
K
H
K
W
Dog
Lupus familis
XP_549005
393
44984
R244
N
D
T
H
K
S
V
R
K
A
T
F
H
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q07105
441
49630
R289
G
Q
A
G
V
A
A
R
P
V
K
E
E
A
I
Rat
Rattus norvegicus
P49001
393
44364
S244
S
K
R
H
V
R
I
S
R
S
L
H
Q
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510645
359
41050
R210
S
S
S
R
A
P
W
R
G
T
A
A
S
E
A
Chicken
Gallus gallus
Q90752
405
46039
R256
G
K
H
V
R
I
S
R
S
L
P
Q
G
H
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P85857
404
46271
F255
S
K
K
R
E
N
L
F
N
E
M
K
E
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
H419
S
L
K
P
A
P
H
H
H
V
R
L
R
R
S
Honey Bee
Apis mellifera
XP_001122815
374
42068
N224
K
R
N
I
N
E
R
N
D
T
W
V
V
N
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
S246
I
K
E
L
G
A
I
S
K
K
C
T
A
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
50
28.6
N.A.
72
21.5
N.A.
26.4
21.8
N.A.
21.1
N.A.
21.7
21.3
N.A.
20.2
Protein Similarity:
100
99.1
54.1
45.1
N.A.
80.6
39.2
N.A.
44.2
38.3
N.A.
39.6
N.A.
36.9
40.3
N.A.
39.4
P-Site Identity:
100
100
0
6.6
N.A.
40
6.6
N.A.
6.6
0
N.A.
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
13.3
13.3
N.A.
60
26.6
N.A.
6.6
26.6
N.A.
40
N.A.
26.6
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
17
17
25
0
0
9
9
9
9
25
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
0
0
0
0
9
0
% D
% Glu:
0
17
9
0
9
9
0
9
0
9
0
25
34
9
9
% E
% Phe:
9
0
9
0
0
0
9
9
9
0
0
9
0
0
0
% F
% Gly:
17
0
0
9
9
0
0
0
9
9
17
0
9
0
9
% G
% His:
0
0
9
17
0
0
9
9
9
0
0
9
17
9
0
% H
% Ile:
9
0
0
9
0
9
17
0
0
0
0
0
0
0
17
% I
% Lys:
9
34
17
0
9
0
0
0
17
9
17
17
0
17
0
% K
% Leu:
0
9
0
9
17
0
9
0
0
9
9
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
9
9
9
9
0
9
9
0
0
0
0
17
0
% N
% Pro:
0
0
0
9
0
17
0
0
25
0
9
0
0
9
0
% P
% Gln:
17
9
0
0
0
9
0
0
0
0
0
9
9
0
0
% Q
% Arg:
0
9
25
17
9
9
9
34
9
0
9
0
9
9
17
% R
% Ser:
34
9
9
17
9
25
9
17
9
9
0
0
9
0
9
% S
% Thr:
0
9
9
0
0
0
0
0
0
17
9
9
0
0
0
% T
% Val:
0
0
0
9
17
0
9
0
0
34
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _